Babban Tsabta 540737-29-9 Tofacitinib citrate don JAK Pathway Inhibitor

Takaitaccen Bayani:

Tsafta:≧99.0%

Matsayin Inganci:Matsayin Kasuwanci ko kuma yadda ake buƙata

Iyawa:35Kgs/wata

Rayuwar Shelf:Shekaru Uku

Aikace-aikace:Magance cututtuka na rheumatoid, psoriatic arthritis, ankylosing spondylitis da ulcerative colitis.

Amfanin Ƙungiya:Ƙwararrun tallace-tallacen tallace-tallace na fitarwa tare da horarwar sana'a a masana'anta

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Tags samfurin

Samfurasuna	Tofacitinib Citrate
Makamantu	(3R,4R) -1- (Cyanoacetyl) -4-methyl-N-methyl-N-1H-pyrrolo [2,3-d] pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3 - propanetricarboxylate;CP 690500-10;CP 690550-10;(3R,4R) -4-Methyl-3- (methyl-7H-pyrrolo [2,3-d] pyrimidin-4-ylamino) -beta-oxo-1-piperidinepropanenitrile 2-Hydroxy-1,2,3-propanetricarboxylate
CAS No.	540737-29-9
Bayyanar	Kashe fari zuwa fari foda
Tsarin kwayoyin halitta	C₁₆H₂₀N₆OC₆H₈O₇
Nauyin Kwayoyin Halitta	504.50
Aikace-aikace	Matsayin magunguna ko manufar bincike
Shiryawa	Kamar yadda kuka bukata
Adana	Ajiye a cikin matsi, kwantena masu jure haske a wuri mai sanyi

Tofacitinib Citrate (CAS #)540737-29-9)
ABUBUWA	Ma'auni	SAKAMAKO
Bayyanar	Kashe fari zuwa fari foda	Kashe farin foda
Ganewa	HPLC;IR;HNMR	Ya bi
Solubility	Mai narkewa a cikin DMSO a 100mg/ml, mai narkewa sosai a cikin ethanol, mai narkewa cikin ruwa da dai sauransu.	Ya bi
Asara akan bushewa	≤0.5%	0.12%
Ragowa akan kunnawa	≤0.1%	0.05%
Karfe masu nauyi	≤10pm	Ya bi
Abubuwa masu alaƙa	Diastereomer (RS+SR) ≤0.1% Rashin Tsabtace Guda ≤0.15% Jimlar ƙazanta ≤1.0%	0.05% 0.14% 0.18%
Enantiomorphism Isomers	≤0.2%	Ya bi
Ragowar Magani	Ethanol ≤5000ppm Methanol ≤3000ppm Toluene ≤890ppm	Ya bi
Citrate abun ciki	36.2% ~ 40%	37.8%
Tsafta	≥99.0%	99.38%
Assay	60.68% ~ 63.16% na Tofacitinib INN 98% ~ 102% na Tofacitinib Citrate INN	62.04% 99.12%
Kammalawa: Ya cika

Bayanin Kamfanin

√ Cikakken ƙwarewar gudanarwa a masana'anta da ƙwararrun masu bin fasaha;
√ Quality ne ko da yaushe mu saman la'akari, M QC tsarin;
√ 11 shekaru gogaggen fitar da tallace-tallace tawagar;
√ R&D mai zaman kansa;
√ Biyu da aka sanya hannu na dogon lokaci na GMP;
√ wadataccen albarkatu na masana'antu marasa aiki da yawa don aikin da aka keɓance;
√ Ƙwararren aiki mai inganci tare da madaidaiciyar hanya.
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